Looks like someone is one step ahead of me in the examination of Flaw #3 (Assumed Path of Positive Mutations), I’ll try to post on this sometime next week (probably the weekend). Although the researchers try to put a positive spin on this news, it is actually quite detrimental to their case (and it should come as no surprise to anyone, really).

Anyway, on to the story:

Darwinian evolution follows very few of the available mutational pathways to attain fitter proteins, researchers at Harvard University have found in a study of a gene whose mutant form increases bacterial resistance to a widely prescribed antibiotic by a factor of roughly 100,000. Their work indicates that of 120 harrowing, five-step mutational paths that theoretically could grant antibiotic resistance, only about 10 actually endow bacteria with a meaningful evolutionary advantage.